ACTIVITY NUMBER:  MD030
ACTIVITY TITLE: Third Party Reproduction - Gamete and Embryo Donation and Gestational Carrier Use

The American Society for Reproductive Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

The American Society for Reproductive Medicine designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credit™. Physicians should only claim credit commensurate with the extent of their participation in the activity.

Release Date: July 1, 2016
Reviewed:  February 10, 2025
Expiration Date: February 9, 2028

Estimated Time to Complete Activity: 1.0 hour

In most cases, offspring result from a man and woman producing gametes that lead to conception in the mother’s uterus. However, the term "parent" may take on new meaning. Third-party reproduction has made it possible for infertile couples to have more choices in building a family. Third party reproduction can involve one or more third parties including an oocyte donor and recipient, sperm donor and recipient, embryo donor or recipient, and surrogates and gestational carrier, and the partners of these individuals. While some procedures are accomplished with little intervention, many approaches include the use of assisted reproductive technologies (ART), such as in vitro fertilization. This area has been identified as a physician practice gap for reproductive care physicians based on recent competence assessments by the American Society for Reproductive Medicine.

This educational activity provides an overview of the clinical aspects involved in providing alternative approaches to parenting through third party reproduction based on current regulations and practice guidelines.

At the conclusion of the educational activity, participants should be able to:

1. Define third party reproduction.
2. Describe recommended screening, informed consent, compensation and cycle synchronization for oocyte donors.
3. Describe recommended screening, informed consent, compensation and cycle synchronization for therapeutic donor insemination.
4. Identify the guidelines for embryo donation.
5. Identify the guidelines for and types of surrogacy.

This activity has been designed to meet the educational needs of physicians and allied health professionals who care for women from adolescence to postmenopause.

Medical Knowledge

Patient Care

Successful completion of this activity requires the learner to:

• View a course overview page, containing all CME and disclosure information, including acknowledgement of commercial support and disclosure of unlabeled use, prior to the start of each module.

• Complete a 10-question pre-exam prior to the module. Learners should note any pre-exam questions answered incorrectly for clarification during module study.

• Be given the option of downloading a printed syllabus containing the presentation and narrative.
• Participate in the interactive activity: Audio narration is synchronized with PowerPoint presentation that can be advanced, stopped or reversed as desired.
• Complete a 10-question post-exam, with feedback of correct/incorrect answers, scoring a minimum of 70% in two attempts.
• Complete the evaluation survey.
• Print certificate of completion.

• Ruben Alvero, MD - Consultant: Cooper Surgical
• Jodie L. Asher – Employee: Integrated Genetics
• Valerie L. Baker – Institutional Support from IBSA
• Samantha Butts, MD - Nothing to Disclose
• Bruce Carr, MD – Grant/Research: Evofem, Abbott, Medicines360, Merck
• Charles C. Coddington, MD - Ownership/Stock: Gilead, Proctor and Gamble, Merck
• William Catherino, MD – Research/Speaker for EMD Serono; Grant/Research for Bayer and Schering Pharma
• Owen K. Davis, MD – Nothing to Disclose
• Michael Eisenberg, MD – Consultant: Sandstone Diagnostics, Reprovantage, Galapagos, Abbvie
• Leslie Francis, JD, PhD – Independent Contractor and Advisory Board for Amgen
• Elizabeth Grill, PsyD - Nothing to Disclose
• Clarisa Gracia, MD - Nothing to Disclose
• Emily Jungheim, MD – Consultant: Abbvie, Genentech, Spectrum Pharmaceuticals, Celgene
• Sigal Klipstein, MD – Nothing to Disclose
• Sacha Krieg M.D.,Ph.D. – Nothing to Disclose
• Benjamin Lannon, MD - Stock ownership: Dyax Corporation
• Mark Licht, MD - Nothing to Disclose
• Janet McLaren Bouknight, MD - Nothing to Disclose
• Samantha M. Pfeifer, MD – Consultant: Best Doctors
• Thomas Price, MD – Grant/Research: Bayer Pharmaceutical, Vivere Health; Consultant: GuidePoint, MedaCorp, Gerson Lehman Group, Best Doctors Consultant
• Gail S. Prins, PhD, HCLD - Nothing to Disclose
• Elizabeth Puscheck, MD - Research Grants for Wyeth and Ethicon
• Richard H. Reindollar, MD – Nothing to Disclose
• Ginny L. Ryan, MD, MA - Nothing to Disclose
• Jay Sandlow, MD - Nothing to Disclose
• David Shin, MD - Speaker's Bureau: Endo Pharmaceutical
• James F. Smith, MD - Nothing to Disclose
• Steven J. Sondheimer, MD – Speakers Bureau: Schering-Plough/Merck, Bayer
• Laurel Stadtmauer, MD – Speakers Bureau: Watson Pharmaceuticals
• Helen Tempest, PhD – Nothing to Disclose
• Michael A. Thomas, MD – Consultant for Watson Pharmaceuticals; Grant/research: Ferring, Medicines 360, Berlex, EvoFem
• Thomas Toth, MD – Consultant: Good Start Genetics
• Angela Trepanier, MS, CGC – Nothing to Disclose
• Carin Yates, MS, CGC - Nothing to Disclose
• Eric Widra, MD – Stock Ownership – SG Patent Holdings, LLC; Consultant: Natera, Counsyl

It is the policy of the ASRM to ensure balance, independence, objectivity, and scientific rigor in all its educational activities. All faculty/authors participating in this activity were required to disclose any relationships they may have with commercial entities whose products or services are used to treat patients so that participants may evaluate the objectivity of the presentations. The content and views presented in this activity are those of the faculty/authors and do not necessarily reflect those of the ASRM. Any discussion of off-label, experimental, or investigational use of drugs or devices will also be disclosed. The disclosure statements were reviewed by the Subcommittee for Standards of Commercial Support of the CME Committee of ASRM and any perceived conflicts of interest were resolved in accordance with the policies of the ACCME.

This CME activity is sponsored by the American Society for Reproductive Medicine.

This program is supported by an educational grant from Schering Corporation, a subsidiary of Merck & Co., Inc.