Meeting Details

Mosaicism in Humans
Expiration Date:
October 15, 2020
0.50 AMA PRA Category 1 Credit(TM)
0.00 Certificate of Completion
0.50 Non-physician CME Credits

Chromosomal mosaicism, the presence of two distinct cell lines, is prevalent throughout human pre- and postimplantation development and can lead to genetic abnormalities, miscarriages, and stillbirths.  Mosaicism is derived from a variety of mechanisms including nondisjunction, anaphase lagging, and endoreplication.  Mosaicism can be caused by any one of numerous factors from paternal, maternal, or exogenous factors such as culture media or ovarian hyperstimulation as is needed during in vitro fertilization.  The clinical consequences of mosaicism depend on what chromosome is involved, when, and where an error occurs, with meiotic errors typically leading to general mosaicism and mitotic errors at specific cell lineage points typically leading to confined mosaicism.   This educational activity provides a review of the origins, mechanisms, incidence, and clinical consequences of chromosomal mosaicism in humans.

  • List Price: $14.00 USD
  • Member Price: Free

ACTIVITY TITLE: Mosaicism in Humans



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